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Sequential Pancreaticoduodenectomy after Living Donor Liver Transplantation for Cholagiocacinoma
Author(s) -
Soejima Y.,
Ueda S.,
Sanefuji K.,
Kayashima H.,
Yoshizumi T.,
Ikegami T.,
Yamashita Y.,
Sugimachi K.,
Iguchi T.,
Taketomi A.,
Maehara Y.
Publication year - 2008
Publication title -
american journal of transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 188
eISSN - 1600-6143
pISSN - 1600-6135
DOI - 10.1111/j.1600-6143.2008.02346.x
Subject(s) - medicine , pancreaticoduodenectomy , liver transplantation , surgery , primary sclerosing cholangitis , concomitant , complication , transplantation , living donor liver transplantation , disease , resection
Liver transplantation (LT) for patients with primary sclerosing cholangitis (PSC) is often contraindicated due to concomitant occurrence of cholangiocarcinoma (CC). Cases of simultaneous pancreaticoduodenectomy (PD) with LT have been sporadically reported; however, the applicability of such an invasive procedure to patients with CC has not been validated. We report here a case of sequential PD performed 44 days after a successful living donor liver transplantation (LDLT) using a left lobe graft. Although a clear pancreatic juice leakage through the drain persisted for days after surgery, the patient recovered from the complication and was discharged 32 days after the procedure. Currently, 1 year after LDLT, the patient is doing well with no evidence of recurrence. In conclusion, a sequential PD following LDLT is a safe and feasible option to treat CC complicating PSC. Long‐term follow‐up and accumulation of cases are necessary to evaluate the effectiveness of this procedure for this complicated disease.