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Increased Vascular Resistance and Not Salt Retention Characterizes Cyclosporine A–Induced Hypertension: Report in an Anuric Patient
Author(s) -
Wahba I. M.,
Bennett W. M.
Publication year - 2007
Publication title -
american journal of transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 188
eISSN - 1600-6143
pISSN - 1600-6135
DOI - 10.1111/j.1600-6143.2007.01871.x
Subject(s) - medicine , vascular resistance , pathophysiology of hypertension , hemodialysis , cardiology , intensive care medicine , urology , blood pressure , hemodynamics
Cyclosporine A (CsA) use is associated with hypertension in most solid‐organ transplant recipients. The mechanisms of CsA‐induced hypertension have not been fully elucidated and are still controversial. We present a case of CsA‐induced hypertension who was anuric and receiving hemodialysis, and in whom noninvasive cardiothoracic bioimpedence revealed elevated systemic vascular resistance without evidence of fluid‐volume overload. We briefly discuss the possible mechanisms of CsA‐induced hypertension in light of this information.