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Postrenal Transplant Non‐EBV Multiple Myeloma of Donor Origin
Author(s) -
Peri N.,
Kussick S.,
Bakthavatsalam R.,
Mitsumori L.,
Dighe M.
Publication year - 2006
Publication title -
american journal of transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 188
eISSN - 1600-6143
pISSN - 1600-6135
DOI - 10.1111/j.1600-6143.2005.01170.x
Subject(s) - multiple myeloma , medicine , fluorescence in situ hybridization , transplantation , kidney transplantation , kidney , epstein–barr virus , pathology , virus , chromosome , immunology , gene , genetics , biology
Multiple myeloma occurring after solid organ transplantation is a rare condition, with only a few case reports found in the literature. We report a case of Epstein‐Barr virus‐negative, posttransplant multiple myeloma in a 67‐year‐old female, presenting 18 months after renal transplantation. Interestingly, fluorescence in situ hybridization analysis of the tumor revealed a Y chromosome in the majority of the cells, indicating that the neoplasm was derived from the donor kidney. To our knowledge, this represents the first reported case with these features.