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Intestinal Transplantation for Chronic Intestinal Pseudo‐Obstruction in Adult Patients
Author(s) -
Masetti Michele,
Benedetto Fabrizio Di,
Cautero Nicola,
Stanghellini Vincenzo,
Giorgio Roberto De,
Lauro Augusto,
Begliomini Bruno,
Siniscalchi Antonio,
Pironi Loris,
Cogliandro Rosanna,
Pinna Antonio D.
Publication year - 2004
Publication title -
american journal of transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 188
eISSN - 1600-6143
pISSN - 1600-6135
DOI - 10.1111/j.1600-6143.2004.00436.x
Subject(s) - medicine , intestinal failure , parenteral nutrition , transplantation , complication , surgery , population , gastroenterology , environmental health
Intestinal transplantation (ITx) has become a life‐saving procedure for patients with irreversible intestinal failure who can no longer be maintained on parenteral nutrition (PN). This report presents the results of our experience on ITx in patients suffering from chronic intestinal pseudo‐obstruction (CIPO). Between December 30, 2000 and May 30, 2003 six adult patients affected by CIPO underwent primary ITx at our Center. Pre‐transplant evaluation, indication for ITx and surgical technique are reported. On December 30 2003, the mean follow‐up was 25.0 months. No peri‐operative deaths occurred in the study population and five out of six patients are alive, with 1‐year patient and graft survival of 83.3% and 66.6%. Although our series is limited by the number of patients, our experience suggests that ITx transplantation should be considered in adult patients suffering from CIPO and PN life‐threatening complication.