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Are Criteria for Islet and Pancreas Donors Sufficiently Different to Minimize Competition?
Author(s) -
Ris Frédéric,
Toso Christian,
Veith Florence Unno,
Majno Pietro,
Morel Philippe,
Oberholzer José
Publication year - 2004
Publication title -
american journal of transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 188
eISSN - 1600-6143
pISSN - 1600-6135
DOI - 10.1111/j.1600-6143.2004.00409.x
Subject(s) - islet , medicine , pancreas transplantation , pancreas , transplantation , islet cell transplantation , diabetes mellitus , endocrinology , kidney transplantation
Islet and pancreas transplantation may compete for a limited number of organs. We analyzed records from the national Swiss transplant registry during a 4‐year period to investigate the proportion of donors that are suitable for islet and pancreas transplantation. Suitability for pancreas transplantation was mainly defined as: age 10–45 years; weight ≤ 80 kg; BMI ≤ 25 kg/m 2 ; amylasemia ≤ 150 U/l; ICU stay ≤ 3 daysand absence of severe hypotension (MAP ≤ 60 mmHG). Between 1.1.1997 and 31.12.2000, data of 407 donors were collected, from which 321 donors were included in the study. Thirty‐three (10%), 143 (45%), and 23 (7%) donors fulfilled the criteria for pancreas, islet transplantation, and both procedures, respectively. Giving priority to pancreas transplantation and accepting the absence of one selection criterion, 90 (28%) pancreas and 100 (31%) islet donors were identified. We conclude that with current allocation policies prioritizing pancreas transplantation, pancreas and islet transplantation may coexist with little competition.