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Hormonal Contraception and HIV‐1 Transmission
Author(s) -
Blish Catherine A.,
Baeten Jared M.
Publication year - 2011
Publication title -
american journal of reproductive immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.071
H-Index - 97
eISSN - 1600-0897
pISSN - 1046-7408
DOI - 10.1111/j.1600-0897.2010.00930.x
Subject(s) - hormonal contraception , medicine , transmission (telecommunications) , family planning , human immunodeficiency virus (hiv) , hormone , population , gynecology , obstetrics , immunology , physiology , environmental health , research methodology , computer science , telecommunications
Citation Blish CA, Baeten JM. Hormonal contraception and HIV‐1 transmission. Am J Reprod Immunol 2011; 65: 302–307 Safe and effective contraceptive choices are essential for women with HIV‐1 infection and at risk for HIV‐1 infection. Epidemiological and laboratory‐based studies suggest that hormonal contraception may influence HIV‐1 transmission. Several large studies in high‐risk populations indicate that hormonal contraceptive use may modestly increase the risk of HIV‐1 acquisition. In addition, HIV‐1‐infected users of hormonal contraceptives may be more infectious to their uninfected partners, although no studies have directly measured HIV‐1 transmission risk from women to men. However, several studies failed to demonstrate a link between contraceptive use and HIV‐1 acquisition or transmission, and interpretation of many studies limited by methodological considerations, such as infrequent measurements of contraceptive exposure and HIV‐1 status. As a result, many questions remain, and high‐quality studies remain needed. It is clear that hormonal contraceptives are not protective against HIV‐1 infection and that dual protection with condoms should be the goal for women using hormonal contraception.