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Lymphocytes—Their Possible Endocrine Role in the Regulation of Fertility
Author(s) -
Shahani D. Savitri K.,
Gupta Sadhana M.,
Meherji Pervin K.
Publication year - 1996
Publication title -
american journal of reproductive immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.071
H-Index - 97
eISSN - 1600-0897
pISSN - 1046-7408
DOI - 10.1111/j.1600-0897.1996.tb00001.x
Subject(s) - prolactin , endocrine system , infertility , endocrinology , lymphocyte , medicine , fertility , sterility , secretion , hormone , biology , pregnancy , population , environmental health , genetics
PROBLEM: Peptide secretion by peripheral lymphocytes obtained from fertile and infertile women. METHOD: LH, FSH, and prolactin were estimated in the serum and culture supernatants obtained from Con‐A stimulated human lymphocytes by RIA. RESULTS: The levels of LH, FSH and prolactin were low in the culture supernatants obtained from lymphocytes of infertile women, when compared with proven fertile women. CONCLUSION: The results indicated impairment in endocrine functions of lymphocytes obtained from infertile women. This impairment in lymphocyte function could be one of the causes of infertility in these women.