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Immunological Factors in Infertility
Author(s) -
SHUSHAN ASHER,
SCHENKER JOSEPH G.
Publication year - 1992
Publication title -
american journal of reproductive immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.071
H-Index - 97
eISSN - 1600-0897
pISSN - 1046-7408
DOI - 10.1111/j.1600-0897.1992.tb00816.x
Subject(s) - infertility , medicine , unexplained infertility , gynecology , female infertility , andrology , biology , immunology , pregnancy , genetics
Immune infertility can result from destruction of gametes by antisperm antibodies (ASA) or anti‐ovary antibodies, by inhibition of sperm‐zona pellucida binding by ASA, or by prevention of embryo cleavage and early development. Condoms, immunosuppressive therapy, sperm processing, and intrauterine insemination have been widely applied, but with controversial results.