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The Clinical Potential of Recombinant Human Interleukin 4 and Alfa‐2b Interferon
Author(s) -
TROTTA PAUL P.
Publication year - 1991
Publication title -
american journal of reproductive immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.071
H-Index - 97
eISSN - 1600-0897
pISSN - 1046-7408
DOI - 10.1111/j.1600-0897.1991.tb01079.x
Subject(s) - recombinant dna , interferon , interferon alfa , interleukin , biology , immunology , interleukin 4 , cytokine , alpha interferon , genetics , gene
ABSTRACT: Recombinant human interleukin 4 and alfa‐2b interferon (Intron A) exhibit multiple biological effects on cells of diverse origin. Interleukin 4 can affect the growth, differentiation and functional activity of lymphoid and myelomonocytic cells. Alfa‐2b interferon expresses a broad spectrum of antiviral, immunomodulatory, and antiproliferative activities. These properties suggest a broad clinical application for both cytokines.