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Interleukin Production by Human Colostral Cells After In Vitro Mitogen Stimulation
Author(s) -
NIKOLOVA E.,
STAYKOVA M.,
RAICHEVA D.,
KARADJOVA M.,
NERONOV A.,
IVANOV I.,
GORANOV I.
Publication year - 1990
Publication title -
american journal of reproductive immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.071
H-Index - 97
eISSN - 1600-0897
pISSN - 1046-7408
DOI - 10.1111/j.1600-0897.1990.tb00681.x
Subject(s) - stimulation , in vitro , mitogen activated protein kinase , immunology , biology , chemistry , medicine , microbiology and biotechnology , endocrinology , biochemistry
Human colostral cells were pulsed with PHA, Con A, or LPS and cultivated in serum‐free medium. The culture supernatants were tested for IL‐1 activity in C3H/HeJ thymocyte assay and for IL‐2 activity on human lymphoblasts. The IL‐1 activity was the highest at the 24th h of cultivation and IL‐2 activity at the 48th h of cultivation.