Premium
Monoclonal Antibody GB25 Recognizes Human Villous Trophoblasts
Author(s) -
HSI BAELI,
YHE CHANGJING G.
Publication year - 1986
Publication title -
american journal of reproductive immunology and microbiology
Language(s) - English
Resource type - Journals
eISSN - 1600-0897
pISSN - 8755-8920
DOI - 10.1111/j.1600-0897.1986.tb00049.x
Subject(s) - syncytiotrophoblast , monoclonal antibody , placenta , basal plate (neural tube) , microbiology and biotechnology , cytotrophoblast , antibody , biology , fetus , pregnancy , immunology , genetics
A monoclonal antibody GB25 which was raised against placental syncytiotrophoblast reacted specifically with villous trophoblasts. It recognized syncytiotrophoblast, villous cytotrophoblasts of the first‐trimester placentae, and a majority of the cytotrophoblasts in the chorion laeve, but not the residual cells of cytotrophoblastic shell in the basal plates and the cells in the cytotrophoblastic columns. This antibody will be useful for isolating and differentiating villous from extravillous cytotrophoblasts in the first‐trimester placentae.