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The Effect of Immunoglobulin Occurring on Human Sperm In Vivo on the Human Sperm/Hamster Ova Penetration Assay
Author(s) -
HAAS GILBERT G.,
AUSMANUS MILITZA,
CULP LESLIE,
TURECK RICHARD W.,
BLASCO LUIS
Publication year - 1985
Publication title -
american journal of reproductive immunology and microbiology
Language(s) - English
Resource type - Journals
eISSN - 1600-0897
pISSN - 8755-8920
DOI - 10.1111/j.1600-0897.1985.tb00267.x
Subject(s) - sperm , hamster , andrology , penetration (warfare) , antibody , biology , immunoglobulin g , immunology , microbiology and biotechnology , medicine , operations research , engineering
We selected 91 infertile men who were tested for increased sperm‐associated immunoglobulin and also tested in the human sperm/hamster ova penetration assay. There was a statistically significant association between the presence of increased sperm‐associated IgG alone (p = 0.0218) and both sperm‐associated IgG and A (p = 0.0187) when correlated with the failure to penetrate any hamster ova. There was a trend but no statistical significance when sperm‐associated immunoglobulin A alone was present. There was a trend but no statistical relationship between the presence of sperm‐associated immunoglobulin and the sperm penetration assay when the criteria for normality of the sperm penetration assay was a 15% or greater ovum penetration rate.