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Monoclonal Antibody to Human Cytotrophoblast
Author(s) -
LOKE Y.W.,
DAY SUSAN
Publication year - 1984
Publication title -
american journal of reproductive immunology
Language(s) - English
Resource type - Journals
eISSN - 1600-0897
pISSN - 0271-7352
DOI - 10.1111/j.1600-0897.1984.tb00297.x
Subject(s) - cytotrophoblast , syncytiotrophoblast , monoclonal antibody , trophoblast , antibody , antigen , biology , microbiology and biotechnology , immunology , placenta , pregnancy , fetus , genetics
A monoclonal antibody (18B/A5) has been generated against human first trimester trophoblast membranes which, unlike others so far reported in the literature, reacted only with cytotrophoblast and not with syncytiotrophoblast. Although the identity of the target antigen has not yet been established, the antibody could be a valuable tool for the identification and eventual separation and purification of human cytotrophoblast cells.