Premium
Histocompatibility Antigens in Pregnancy, Abortions, Infertility, Preeclampsia, and Trophoblast Neoplasms
Author(s) -
PATTILLO ROLAND A.
Publication year - 1980
Publication title -
american journal of reproductive immunology
Language(s) - English
Resource type - Journals
eISSN - 1600-0897
pISSN - 0271-7352
DOI - 10.1111/j.1600-0897.1980.tb00007.x
Subject(s) - trophoblast , preeclampsia , infertility , histocompatibility , pregnancy , medicine , antigen , major histocompatibility complex , immunology , gynecology , obstetrics , biology , fetus , human leukocyte antigen , genetics , placenta
The genetic makeup of an individual may determine the capacity of the individual to combat successfully cancer and other disease states, eg abnormal pregnancies, abortions, infertility, and preeclampsia. These factors appear to be based upon the individual's immunogenetics, as histocompatibility‐restricted T‐cell cytotoxicity may be deficient in the observed instances of increased histocompatability between husband and wife found in trophoblast tumor patients and in other instances of abnormal pregnancies.