Premium
Intracellular Membrane Transport Systems in Trypanosoma brucei
Author(s) -
Field Mark C.,
Carrington Mark
Publication year - 2004
Publication title -
traffic
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.677
H-Index - 130
eISSN - 1600-0854
pISSN - 1398-9219
DOI - 10.1111/j.1600-0854.2004.00234.x
Subject(s) - biology , trypanosoma brucei , trypanosoma cruzi , kinetoplastida , endomembrane system , trypanosoma , leishmania , protozoa , intracellular , microbiology and biotechnology , genetics , parasite hosting , gene , protozoal disease , golgi apparatus , malaria , immunology , endoplasmic reticulum , world wide web , computer science
Trypanosomes belong to the order kinetoplastida, an early diverging group of organisms in the eukaryotic lineage. The principal reasons for interest in these organisms are twofold; they provide a superb distant triangulation point from which to assess global features of eukaryotic biology and, more importantly, they are representative of a number of pathogenic parasitic protozoa with a huge public health impact – Trypanosoma brucei , T. cruzi and Leishmania spp. Recent advances in the study of intracellular transport in T. brucei have been considerable, and a fuller picture of the complexity, function and role that the endomembrane system plays in trypanosomes is finally emerging.