Open AccessCutaneous resonance running time is decreased in psoriatic lesions
Author(s) -
Lv Chengzhi,
Song Shunpeng,
Luo Wenhai,
Elias Peter M.,
Man MaoQiang
Publication year - 2012
Publication title -
skin research and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.521
H-Index - 69
eISSN - 1600-0846
pISSN - 0909-752X
DOI - 10.1111/j.1600-0846.2011.00559.x
Subject(s) - psoriasis , medicine , dermatology , stratum corneum , surgery , pathology
Background/aims Psoriasis is characterized by lower stratum corneum ( SC ) hydration and dermal inflammation. Both SC hydration and cutaneous inflammation influence cutaneous resonance running time ( CRRT ). However, the characteristics of CRRT in psoriatic lesions are largely unknown. In the present study, we assessed whether changes in CRRT occur in psoriatic lesions in C hinese. Methods A R eviscometer RVM 600 and Corneometer CM 825 were used to measure CRRT s and SC hydration, respectively, in psoriatic lesions (psoriasis vulgaris) on the extensor of forearm in 111 subjects (58 men, 53 women), aged 23–80 years (50.42 ± 1.23 years). The contralateral uninvolved sites served as control. Results In comparison with contralateral uninvolved sites, CRRT s in psoriatic lesions were reduced significantly in all directions. There was neither gender nor age difference in the extent of reduction in CRRT s. However, the reduction of CRRT s varied with measurement directions. Positive correlations of SC hydration with CRRT s were found at some directions in uninvolved and involved sites in young men whereas CRRT s in psoriatic lesions were not correlated with SC hydration in either aged or young women. Moreover, CRRT at 0–6 o'clock direction was positively correlated with SC hydration in involved sites of aged men. Conclusion Cutaneous resonance running times are decreased in psoriatic lesions. Reduction of CRRT s varies with measurement directions, but not gender or age. Measurement of CRRT s could be another valuable approach to assess the severity of psoriasis and the efficacy of its treatment.