Open AccessFacing up to the imperceptible perspiration. Modulatory influences by diabetic neuropathy, physical exercise and antiperspirant
Author(s) -
XhauflaireUhoda Emmanuelle,
Mayeux Géraldine,
Quatresooz Pascale,
Scheen André,
Piérard Gérald E.
Publication year - 2011
Publication title -
skin research and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.521
H-Index - 69
eISSN - 1600-0846
pISSN - 0909-752X
DOI - 10.1111/j.1600-0846.2011.00523.x
Subject(s) - perspiration , sweat , hyperhidrosis , medicine , sudomotor , diabetic neuropathy , stratum corneum , rest (music) , iontophoresis , endocrinology , dermatology , diabetes mellitus , anesthesia , pathology , psychiatry , radiology
Background: Sweating is variably altered by physical exercise, diabetic neuropathy and antiperspirants. Methods: Skin temperature, skin surface water loss (SSWL), the Corneometer ® average capacitance (CMAC) and skin capacitance mapping (SCM) were measured before and after moderate physical exercise in 20 healthy subjects. The effect of 5% aluminium chloride hexahydrate (ACH) in a water solution was similarly tested. The same assessments were performed in 20 diabetic patients at rest. Results: Diabetic neuropathy appeared at rest as an increased (compensatory) SCM on the forearms without obvious modification on the hypohidrotic legs. On ACH sites after exercise, SCM revealed both a lowered number of active sweat glands and a lighter stratum corneum (SC) (dryness). In addition, CMAC and SSWL were decreased on ACH sites at rest and at completion of exercise. Conclusion: In diabetic neuropathy, the compensatory hyperhidrosis is more easily disclosed than the hypohidrosis. ACH affects both sweat excretion and the SC hydration.