Open AccessOptical coherence tomography in dermatology
Author(s) -
Pagi A.,
Knuettel A.,
Welker P.,
Rist M.,
Stoudemayer T.,
Kolbe L.,
Sadiq I.,
Kligman A. M.
Publication year - 1999
Publication title -
skin research and technology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.521
H-Index - 69
eISSN - 1600-0846
pISSN - 0909-752X
DOI - 10.1111/j.1600-0846.1999.tb00120.x
Subject(s) - optical coherence tomography , tomography , stratum corneum , dermatology , medicine , acne , biomedical engineering , medical physics , optics , pathology , ophthalmology , radiology , physics
Background/alms: Optical coherence tomography is a new in vivo imaging tool originally developed to investigate the eye. We undertook a preliminary investigation of experimental and clinical dermatological applications. Methods: We obtained optical coherence tomography images of ethnic groups, of cutaneous changes induced by exposure to water and dimethyl sulfoxide, of corticosteroid atrophy and of acne vulgaris. Results: Optical coherence tomography was able to visualize specific structural changes in stratum corneum and viable epidermis in these diverse conditions. Conclusions: The high lateral and axial resolution of 4 urn and 7 μm, respectively, and the image quality of this prototype make optical coherence tomography a promising instrument for clinical and investigative dermatology.