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Effects of exercise training on oxygen uptake in coronary heart disease: a systematic review and meta‐analysis
Author(s) -
Valkeinen H.,
Aaltonen S.,
Kujala U. M.
Publication year - 2010
Publication title -
scandinavian journal of medicine and science in sports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.575
H-Index - 115
eISSN - 1600-0838
pISSN - 0905-7188
DOI - 10.1111/j.1600-0838.2010.01133.x
Subject(s) - vo2 max , medicine , aerobic exercise , physical therapy , meta analysis , cardiology , randomized controlled trial , psychological intervention , exercise physiology , heart rate , blood pressure , psychiatry
It is not known to what extent exercise programs increase maximal oxygen uptake (VO 2max ) in patients with coronary heart diseases (CHD). The purpose of this study is to determine the effect of exercise interventions on VO 2max in subjects with CHD. Database search of randomized controlled trials was conducted from PubMed. Studies were included that reported the characteristics and effects of exercise interventions in subjects with CHD, included a non‐exercise control group and measured VO 2max using direct measurement method. Eighteen studies were eligible. Exercise interventions increased VO 2max by 2.6 ± 1.6 and 0.3 ± 1.4 mL/kg/min in the training and control groups, respectively. The net difference in the change of VO 2max between the groups was 2.3 mL/kg/min with a standardized mean difference of 0.60 [95% CI 0.47, 0.74] ( P <0.001). Aerobic training led to a larger difference in VO 2max between the groups than other training modes. Over 6 months of training period and training started within 3 months after a cardiac event also had a significant effect on VO 2max . This analysis showed that a long exercise training period starting soon after a cardiac event improved VO 2max in patients with CHD most effectively. In future studies, the training programs should be designed carefully as even larger improvements in VO 2max may be possible.