Premium
Hyperoxic interval training in chronic obstructive pulmonary disease patients with oxygen desaturation at peak exercise
Author(s) -
Helgerud J.,
Bjørgen S.,
Karlsen T.,
Husby V. S.,
Steinshamn S.,
Richardson R. S.,
Hoff J.
Publication year - 2010
Publication title -
scandinavian journal of medicine and science in sports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.575
H-Index - 115
eISSN - 1600-0838
pISSN - 0905-7188
DOI - 10.1111/j.1600-0838.2009.00937.x
Subject(s) - copd , medicine , hyperoxia , interval training , hypoxemia , cardiology , physical therapy , aerobic exercise , coronary artery disease , vo2 max , quality of life (healthcare) , ventilatory threshold , heart rate , lung , blood pressure , nursing
High‐intensity work might not be preserved in chronic obstructive pulmonary disease (COPD) during whole‐body exercise due to ventilatory limitations that exceed metabolic limitations, resulting in reduced training adaptations. The purpose of the present study was to address the hyperoxic effect during training and testing in COPD patients with hypoxemia at peak exercise. Six COPD and eight coronary artery disease (CAD) patients completed 24 aerobic high‐intensity interval training sessions, 4 × 4 min in hyperoxia at 85–95% of the peak heart rate and peak exercise tested in normoxia and hyperoxia pre‐ and post‐training. VO 2peak increased in the COPD group by 19% (13–31%) and in the CAD group by 15% (7–29%), [0.98(0.68–1.52)–1.17(0.89–1.78) and 2.11(1.57–2.64)–2.44(1.92–3.39) L/min], respectively. VO 2peak was higher in hyperoxia at pre‐ and post‐test (1.22(0.80–1.87) and 1.37(1.01–1.94) L/min) in the COPD group. Work economy improved by 10% in both groups. Quality of life improved in the COPD group in terms of physical and mental health status by 24% and 35%. Hyperoxic aerobic high‐intensity interval training in COPD patients with hypoxemia at peak exercise increases VO 2peak , peak workload, work economy and quality of life. Acute hyperoxia increases VO 2peak , peak workload at pre‐ and post‐test compared with normoxia in the COPD patients, indicating an oxygen supply limitation to VO 2peak .