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Diffusing capacity of the lung for CO and pulmonary blood flow during incremental and intermittent exercise
Author(s) -
Charloux A.,
Enache I.,
Richard R.,
OswaldMammosser M.,
LonsdorferWolf E.,
Piquard F.,
Geny B.
Publication year - 2010
Publication title -
scandinavian journal of medicine and science in sports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.575
H-Index - 115
eISSN - 1600-0838
pISSN - 0905-7188
DOI - 10.1111/j.1600-0838.2009.00924.x
Subject(s) - pulmonary diffusing capacity , diffusing capacity , medicine , cardiology , lung , blood flow , lung volumes , lung function
The aims of this study were to evaluate the feasibility of successive diffusing capacity of the lung for carbon monoxide (D LCO ) measurements during two different exercise tests (upright cycling), and to compare the relationships between D LCO and pulmonary blood flow (Qc). Eight healthy subjects performed an incremental test (1‐min step) and a strenuous 30‐min intermittent‐work exercise test (4 min at low and 2 min at high workload). Intrabreath D LCO and Qc were calculated by assessing the uptake of CO and C 2 H 2 during exhalation. D LCO could be measured reliably up to 73–90% of peak oxygen consumption (VO 2 ) during the incremental test, and up to 85–95% of peak VO 2 during the intermittent test. The coefficients of variation of D LCO and Qc measured during two successive constant‐load exercise tests were 5–6% and 7–11%, respectively. The highest values of D LCO , Qc and VO 2 measured during the incremental and intermittent tests were similar (56 and 51 mL/mmHg/min for D LCO , 18.7 and 18.3 L/min, for Qc and 2.4 and 2.3 L/min for VO 2 , respectively). The main observed result was that the linear relationships between D LCO and Qc were similar whatever the exercise type. This allows D LCO comparisons, with regards to Qc, during different exercise protocols.