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Exploratory laser flash photolysis study of free radical reactions and magnetic field effects in melatonin chemistry
Author(s) -
Scaiano J. C.
Publication year - 1995
Publication title -
journal of pineal research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.881
H-Index - 131
eISSN - 1600-079X
pISSN - 0742-3098
DOI - 10.1111/j.1600-079x.1995.tb00188.x
Subject(s) - flash photolysis , radical , benzophenone , melatonin , photochemistry , chemistry , reaction rate constant , scavenger , photodissociation , kinetics , organic chemistry , medicine , physics , quantum mechanics
Melatonin is an excellent free radical scavenger, reacting with ferf‐butoxyl and cumyloxyl radicals with rate constants of 3.4 × 10 7 and 6.7 × 10 7 M −1 s −1 , respectively. Reaction with benzophenone triplet occurs with a near‐diffusion‐controlled rate constant of 7.6 × 10 9 M −1 s −1 in acetonitrile and probably involves charge transfer. When the radical pair formed by reaction of benzophenone triplet and melatonin is sequestered in a micelle, it is subject to extensive magnetic field effects that can be readily interpreted by the radical pair model.