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Vasoactive Intestinal Peptide‐Like Immunoreactive Nerve Fibers in the Pineal Gland of the Sheep
Author(s) -
Cozzi Bruno,
Mikkelsen Jens D.,
Merati Danila,
Capsoni Simona,
Møller Morten
Publication year - 1990
Publication title -
journal of pineal research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.881
H-Index - 131
eISSN - 1600-079X
pISSN - 0742-3098
DOI - 10.1111/j.1600-079x.1990.tb00805.x
Subject(s) - vasoactive intestinal peptide , pinealocyte , pineal gland , capsule , parenchyma , anatomy , melatonin , ganglion , biology , superior cervical ganglion , endocrine gland , endocrinology , medicine , chemistry , pathology , neuropeptide , receptor , botany , thyroid
Vasoactive intestinal peptide (VIP)‐like immunoreactive nerve fibers were demonstrated by peroxidase antiperoxidase (PAP) inmmunohistochemistry to be distributed throughout the entire pineal gland of the sheep. VIP‐containing fibers were observed along the blood vessels, penetrating into the gland from the pial capsule and also in the capsule itself. Some fibers left the perivascular position and entered the pineal parenchyma, where they were located among pinealocytes. This suggested that the VIPergic fibers might influence both pinealocytes and blood vessels of the gland. The location of VIP‐containing fibers in the capsule of the pineal gland indicates that the fibers originate from perikarya located in a peripheral ganglion.