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Hypothalamic and Neurohypophysial Vasopressin and Oxytocin in Melatonin‐Treated Pinealectomized Male Rats
Author(s) -
Juszczak Marlena,
Guzek Jan W.
Publication year - 1988
Publication title -
journal of pineal research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.881
H-Index - 131
eISSN - 1600-079X
pISSN - 0742-3098
DOI - 10.1111/j.1600-079x.1988.tb00797.x
Subject(s) - pinealectomy , vasopressin , oxytocin , medicine , endocrinology , melatonin , hypothalamus , neuropeptide , neurohormones , biology , chemistry , pineal gland , hormone , receptor
The effect of melatonin on hypothalamic and neurohypophysial vasopressin and oxytocin was investigated in normal and pinealectomized rats. Pinealectomy was followed by a decrease of both vasopressin and oxytocin content in the hypothalamus and neurohypophysis. In unpinealectomized rats, melatonin decreased vasopressin and oxytocin storage in the hypothalamo‐neurohypophysial system. Following pineal removal, melatonin did not augment the pinealectomy‐induced decrease of vasopressin and oxytocin in the neurohypophysis; the hypothalamic storage of both neurohormones was even higher when compared with vehicle‐treated animals.