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Validation of skin surface microtopography as a measure of skin photoaging in a subtropical population aged 40 and over
Author(s) -
Hughes Maria Celia,
Strutton Geoffrey M.,
Fourtanier Anny,
Green Adèle C.
Publication year - 2012
Publication title -
photodermatology, photoimmunology and photomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.736
H-Index - 60
eISSN - 1600-0781
pISSN - 0905-4383
DOI - 10.1111/j.1600-0781.2012.00661.x
Subject(s) - photoaging , medicine , odds ratio , confidence interval , logistic regression , skin aging , dermatology , population , pathology , environmental health
Summary Background Evidence suggests that skin surface microtopography is a valid measure of photoaging among young adults, but whether this applies to older adults is unknown. Methods We investigated the association between degree of photoaging as measured by histological dermal elastosis and skin microtopography grades by decade of age from 40 to 89 years in a community sample in A ustralia. Skin surface replicas and punch biopsies were taken from 664 participants of the N ambour S kin C ancer S tudy. The association was assessed using ordinal logistic regression with proportional odds assumption, using histological dermal elastosis grades as outcome. Results There was significant increase in odds of higher skin surface microtopography grades with higher dermal elastosis grades for age groups below 70 years [40 to 49 years: odds ratio ( OR ) 2.96, 95% confidence interval ( CI ) 1.68–5.22; 50 to 59 years: OR 3.78, 95% CI 2.28–6.26; 60 to 69 years: OR 2.47, 95% CI 1.41–4.35). The association was not significant for those 70 years or older. Conclusion Skin surface microtopography grading system is a valid measure of degree of dermal elastosis for middle‐aged and older adults up to 69 years but appears not to be valid for adults 70 years or more living in a high sun exposure setting.