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Successful treatment of cutaneous leishmaniasis with intralesional aminolevulinic acid photodynamic therapy
Author(s) -
Evangelou George,
Krasagakis Konstantin,
Giannikaki Elpida,
KrugerKrasagakis Sabine,
Tosca Androniki
Publication year - 2011
Publication title -
photodermatology, photoimmunology and photomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.736
H-Index - 60
eISSN - 1600-0781
pISSN - 0905-4383
DOI - 10.1111/j.1600-0781.2011.00610.x
Subject(s) - photodynamic therapy , cutaneous leishmaniasis , leishmaniasis , dermatology , medicine , leishmania , immunology , chemistry , parasite hosting , organic chemistry , world wide web , computer science
Leishmaniasis is a protozoan infectious disease that often affects the skin and may acquire a chronic and difficult to treat course. Topical photodynamic therapy (PDT) is a novel treatment which involves the selective uptake of a photosensitizing agent. Exposure to an appropriate light source in the presence of oxygen leads to formation of reactive oxygen species and destruction of the target cells. We report on the successful treatment of a 69‐year‐old patient with a relapse of long‐standing cutaneous leishmaniasis using intralesional aminolevulinic acid‐PDT.

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