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Unsuccessful treatment of recalcitrant cutaneous discoid lupus erythematosus with photodynamic therapy
Author(s) -
RomeroMaté Alberto,
CastañoSuárez Esther,
GarcíaDonoso Carmen,
MartínezMorán Cristina,
MeseguerYebra Carmen,
Borbujo Jesús
Publication year - 2010
Publication title -
photodermatology, photoimmunology and photomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.736
H-Index - 60
eISSN - 1600-0781
pISSN - 0905-4383
DOI - 10.1111/j.1600-0781.2010.00506.x
Subject(s) - acitretin , medicine , dermatology , azathioprine , dapsone , photodynamic therapy , discoid lupus erythematosus , methotrexate , thalidomide , auranofin , lupus erythematosus , surgery , psoriasis , immunology , rheumatoid arthritis , disease , multiple myeloma , chemistry , organic chemistry , antibody
Discoid lupus erythematosus (DLE) can be a therapeutic challenge. Antimalarials and topic steroids are the first‐line standard therapies, while systemic steroids, immunomodulators (as azathioprine, methotrexate, cyclosporine), retinoids (acitretin), thalidomide, auranofin and dapsone are used as second‐line therapies. We report two patients with recalcitrant DLE who were treated with three and two sessions of 5‐aminolevulinic photodynamic therapy without an improvement and with a bad tolerance to the therapy.