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p53 protein expression in skin with different levels of photoaging
Author(s) -
De Castro Inês Alencar,
Schütz Larissa,
Capp Edison,
Cartell André,
Meurer Luise,
Bakos Lucio
Publication year - 2009
Publication title -
photodermatology, photoimmunology and photomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.736
H-Index - 60
eISSN - 1600-0781
pISSN - 0905-4383
DOI - 10.1111/j.1600-0781.2009.00400.x
Subject(s) - photoaging , immunohistochemistry , skin cancer , p53 protein , dermatology , p53 expression , medicine , melanoma , protein expression , cancer , cancer research , chemistry , gene , biochemistry
In non‐melanoma skin cancer, keratinocytes show marked p53 protein expression. Considering photoaging as a background for skin cancer, p53 protein expression by immunohistochemistry was evaluated in normal skin with different levels of photoaging. The difference in p53 expression between mild and severe levels of photoaging was not statistically significant ( P =0.169).