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Dapsone‐induced photosensitivity: a rare clinical presentation
Author(s) -
Kar Bikash Ranjan
Publication year - 2008
Publication title -
photodermatology, photoimmunology and photomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.736
H-Index - 60
eISSN - 1600-0781
pISSN - 0905-4383
DOI - 10.1111/j.1600-0781.2008.00372.x
Subject(s) - dapsone , photosensitivity , medicine , leprosy , dermatology , sulfone , adverse effect , pharmacology , chemistry , organic chemistry , materials science , optoelectronics
Dapsone is an efficient anti‐inflammatory and antimycobacterial agent. It is one of the main constituents of multidrug therapy (MDT). It acts by interference with folate metabolism. Dapsone‐induced photosensitivity is a rare, non‐dose‐related adverse effect of the sulfone and can occur in patients with inflammatory skin disorders treated with dapsone. So far, only 12 cases seem to have been reported in the literature. We report a case of dapsone‐induced photosensitivity in an Indian patient with leprosy.