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UVA1 phototherapy for cutaneous diseases: an experience of 92 cases in the United States
Author(s) -
Tuchinda Chanisada,
Kerr Holly A.,
Taylor Charles R.,
Jacobe Heidi,
Bergamo Bettany M.,
Elmets Craig,
Rivard Jennifer,
Lim Henry W.
Publication year - 2006
Publication title -
photodermatology, photoimmunology and photomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.736
H-Index - 60
eISSN - 1600-0781
pISSN - 0905-4383
DOI - 10.1111/j.1600-0781.2006.00245.x
Subject(s) - medicine , dermatology , erythema , adverse effect , atopic dermatitis , surgery
Background: The efficacy and safety of UVA1 (340–400 nm) phototherapy were established by studies from European countries. Purpose: Evaluate experience with UVA1 phototherapy for patients with cutaneous diseases in the United States. Methods: A retrospective analysis of 92 cases of UVA1‐treated cutaneous conditions from four medical centers in the United States was performed. Results: Two‐third of the patients showed a fair to good response (26–100% improvement) and one‐third of the patients showed a poor response (0–25% improvement). Diseases with a moderate to good response (51–100% improvement) included scleredema adultorum, hand or foot dermatitis, atopic dermatitis, morphea (medium or medium‐ to high‐dose UVA1), systemic sclerosis, and urticaria pigmentosa. Besides tanning, other adverse effects were found in 15% of patients, which include pruritus, erythema, tenderness, and burning sensation. Patients with skin types I–III responded better that those with a darker skin type. Conclusion: UVA1 phototherapy is a useful and well‐tolerated treatment option for a variety of skin conditions.