Premium
Measurement of suberythema UVA radiation effects on skin by 31 P magnetic resonance spectroscopy
Author(s) -
Zemtsov A.
Publication year - 1997
Publication title -
photodermatology, photoimmunology and photomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.736
H-Index - 60
eISSN - 1600-0781
pISSN - 0905-4383
DOI - 10.1111/j.1600-0781.1997.tb00104.x
Subject(s) - spectroscopy , nuclear magnetic resonance , resonance (particle physics) , radiation , nuclear magnetic resonance spectroscopy , physics , atomic physics , optics , astronomy
31 P magnetic resonance spectroscopy (MRS) scans were obtained from the same anatomical location in four healthy Caucasian individuals before and after 1/2 MED UVA radiation. Suberythema UVA radiation induced in skin production of phosphomonoesters, phosphodiesters, and also depleted phosphocreatine and adenosine triphosphate (ATP). This data seems to indicate that 31 P MRS is a sensitive enough technique to detect UVA induced changes in skin phosphometabolites. Furthermore, this data also appears to indicate that suberythema UVA radiation and dexamethasone induce in skin nearly identical pharmacodynamic effects.