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Systematic review on the effect of rinsing with povidone‐iodine during nonsurgical periodontal therapy
Author(s) -
Sahrmann P.,
Puhan M. A.,
Attin T.,
Schmidlin P. R.
Publication year - 2010
Publication title -
journal of periodontal research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.31
H-Index - 83
eISSN - 1600-0765
pISSN - 0022-3484
DOI - 10.1111/j.1600-0765.2009.01232.x
Subject(s) - scaling and root planing , medicine , iodine , meta analysis , cochrane library , chronic periodontitis , dentistry , saline , randomized controlled trial , adjunctive treatment , confidence interval , treatment modality , periodontitis , chemistry , organic chemistry
Sahrmann P, Puhan MA, Attin T, Schmidlin PR. Systematic review on the effect of rinsing with povidone‐iodine during nonsurgical periodontal therapy. J Periodont Res 2010;.doi: 10.1111/j.1600‐0765.2009.01232.x. © 2009 The Authors. Journal compilation © 2009 Blackwell MunksgaardBackground and Objective: The existing literature is inconsistent regarding whether there is any additional effect of povidone‐iodine (PVP‐iodine) as an adjunctive to scaling and root planing, and, if there is an effect, what its size is. Therefore, the aim of this study was to assess the additional effect of PVP‐iodine as an adjunct to scaling and root planing compared with water, saline or no rinse in the treatment of chronic periodontitis. Material and methods: An electronic literature search of the databases PubMed, EMBASE and the Cochrane Central Library, and a handsearch, were performed (up to November 2008). Two reviewers independently identified and selected screened abstracts for possible inclusion, and assessed randomized, controlled clinical trials comparing the additional benefit of PVP‐iodine with water, saline rinsing or no rinsing in the nonsurgical periodontal therapy of patients with chronic periodontitis. A fixed‐effects meta‐analysis was conducted in the absence of statistically significant heterogeneity. Results: A small, but statistically significant additional beneficial effect of the adjunctive use of PVP‐iodine with enhanced probing pocket depth reductions of 0.28 mm (95% confidence interval: 0.08 to 0.48, p = 0.007) was found. There was no significant heterogeneity between studies ( I 2 = 0%). However, most of the studies included in the meta‐analysis were of low quality, and the treatment modalities showed various differences such as the use of PVP‐iodine at different concentrations and application modalities. Nevertheless, single‐rooted teeth, in particular, showed an additional benefit after scaling and root planing with PVP‐iodine, particularly when the treatment was repeated during the healing stage. Conclusion: The adjunctive use of PVP‐iodine during scaling and root planing may increase the clinical pocket depth reduction, although the clinical significance is small to moderate.