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Toward strategies for the analysis of periodontal disease clinical trials
Author(s) -
Alemayehu D.,
Goldberg J. D.,
Koury K. J.
Publication year - 1992
Publication title -
journal of periodontal research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.31
H-Index - 83
eISSN - 1600-0765
pISSN - 0022-3484
DOI - 10.1111/j.1600-0765.1992.tb01690.x
Subject(s) - clinical trial , periodontal disease , medicine , statistical analysis , disease , dentistry , intensive care medicine , pathology , statistics , mathematics
We consider design, analysis and regulatory issues relating to clinical trials in periodontal disease and identify complications commonly associated with such studies. Alternative statistical procedures that can be used for the analyses of data from periodontal research are reviewed and a case study of the analysis of a Phase II periodontal disease clinical trial is provided to illustrate the use of one of these procedures.