Premium
Attachment of cementum on different hydroxylapatite ceramic (HAC) substrata in vivo . A light and electron microscopic study
Author(s) -
Holtgrave E. A.
Publication year - 1991
Publication title -
journal of periodontal research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.31
H-Index - 83
eISSN - 1600-0765
pISSN - 0022-3484
DOI - 10.1111/j.1600-0765.1991.tb01803.x
Subject(s) - hydroxylapatite , cementum , dental follicle , cementogenesis , cementoblast , chemistry , dentistry , regeneration (biology) , dental cementum , in vivo , materials science , pathology , medicine , biology , mesenchymal stem cell , microbiology and biotechnology , dentin , biochemistry , enzyme
The role of substrate surface characteristics for periodontal regeneration was studied in rats. Cementogenesis was initiated by dental follicle cells retained after dissecting out a molar tooth germ in 5‐day‐old rats. The tooth germ was substituted by a bone replacement material, namely HAC granules of porous consistency. Tissue blocks were removed after 24 weeks and processed for light and electron microscopic examination. On all HAC surfaces a new cementumlike tissue developed, similar to that of natural root surfaces. The results strongly indicate that the exposure of collagen fibers is not essential in order to achieve new periodontal attachment.