Premium
Binding specificity of Fusobacterium nucleatum to human erythrocytes, polymorphonuclear leukocytes, fibroblasts, and HeLa cells
Author(s) -
Ozaki Masaharu,
Miyake Yoichiro,
Shirakawa Masaharu,
Takemoto Toshinobu,
Okamoto Hiroshi,
Suginaka Hidekazu
Publication year - 1990
Publication title -
journal of periodontal research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.31
H-Index - 83
eISSN - 1600-0765
pISSN - 0022-3484
DOI - 10.1111/j.1600-0765.1990.tb01034.x
Subject(s) - fusobacterium nucleatum , hela , fusobacterium , microbiology and biotechnology , chemistry , cell , biology , immunology , bacteria , bacteroides , biochemistry , genetics , porphyromonas gingivalis
Eighteen strains of Fusobacterium nucleatum were studied with respect to their adherence to human erythrocytes, polymorphonuclear leukocytes, fibroblasts, and HeLa cells. Four types of adherence were found: 1) sugar‐sensitive adherence 2) amino acid‐sensitive adherence 3) unknown adherence 4) weak adherence. There was no obvious correlation between the patterns of hemagglutination and adherence to other cells. The results indicate not only a complex network of bacterial receptors on human cells, but also a variety of types of bacterial adherence as expressed by the selectivity of the bacterial binding to specific cell surfaces.