Premium
The efficacy of a new dentifrice in treating dentin sensitivity: Effects of sodium citrate and sodium fluoride as active ingredients
Author(s) -
Clark D. Christopher,
AlJoburi W.,
Chan E. C. S.
Publication year - 1987
Publication title -
journal of periodontal research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.31
H-Index - 83
eISSN - 1600-0765
pISSN - 0022-3484
DOI - 10.1111/j.1600-0765.1987.tb01545.x
Subject(s) - dentifrice , sodium fluoride , dentistry , placebo , medicine , sodium citrate , dentin , toothpaste , citric acid , fluoride , chemistry , food science , inorganic chemistry , alternative medicine , pathology
The purpose of this clinical trial was to study the effectiveness of three new test and one control dentifrice. A total of 120 subjects participated in the study. Measurement of dentin sensitivity consisted of three clinical tests (saturated sucrose solution, cold air blast, and tactile) and a subjective patient assessment. The patients were first stratified by previous treatment attempts and presence of a history of periodontal surgery. Patients were randomly assigned into four groups: 1) dentifrice containing precipitated silica abrasive; 2) dentifrice containing 0.2% sodium citrate buffer in a pluronic gel with precipitated silica abrasive; 3) dentifrice containing 0.2% NaF with precipitated silica abrasive; 4) a formula containing both the 0.2% NaF and the 2% citrate buffer. Neither patients nor examiners were aware of the group assignments. The patients were examined at baseline and after 2 and 4 wk, and 2 months. The efficacy of the new dentifrice system was not established in this investigation nor were the separate efficacies of the major components of the dentifrice. Although subjective and clinical assessments demonstrated a placebo effect, it was present to the same extent for all products, including the placebo.