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Necrotizing ulcerative gingivitis in beagle dogs
Author(s) -
Maltha J. C.,
Mikx F. H. M.,
Kuijpers F. J.
Publication year - 1985
Publication title -
journal of periodontal research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.31
H-Index - 83
eISSN - 1600-0765
pISSN - 0022-3484
DOI - 10.1111/j.1600-0765.1985.tb00836.x
Subject(s) - beagle , pathology , epithelium , connective tissue , junctional epithelium , gingivitis , staining , biology , medicine , dentistry
A new modification of the Warthin spirochete staining method was developed to study at the light microscopic level the distribution of spirochetes in gingival tissues of beagle dogs with induced necrotizing ulcerative gingivitis. Spirochetes were present in cellular exudate at ulcerated sites, in edematous epithelium in the vicinity of ulcerations, and in intact sulcular epithelium. They did not appear to penetrate connective tissues via the ulcerations. These observations suggest that, in the etiology of NUG, spirochetes play a role in the initiation of the pathologic process by penetration of the intercellular spaces in the epithelium.