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Salivary IgA antibody to Actinobacillus actinomycetemcomitans in a young adult population
Author(s) -
Smith Daniel J.,
Ebersole Jeffrey L.,
Taubman Martin A.,
Gadalla Laila
Publication year - 1985
Publication title -
journal of periodontal research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.31
H-Index - 83
eISSN - 1600-0765
pISSN - 0022-3484
DOI - 10.1111/j.1600-0765.1985.tb00404.x
Subject(s) - actinobacillus , saliva , antibody , immunology , periodontal disease , medicine , immunoglobulin a , population , microbiology and biotechnology , biology , periodontitis , immunoglobulin g , environmental health
Stimulated parotid salivas, collected from 162 young adults, were screened in ELISA Tor IgA antibody to Actinobacillus actinomycetemcomitans . Subjects with elevated levels of IgA antibody (HSA) were age‐ and sex‐matched with subjects with low antibody levels (LSA) for subsequent study. Infection with A. actinomycetemcomitans , elevated serum antibody levels to A. actinomycetemcomitans , and presence of multiple sites >5 mm were generally found only in the HSA group. There was a significant association between the presence of deep pockets and elevated serum antibody in these subjects. Thus, screening saliva for IgA antibody may be a useful, noninvasive technique to identify individuals with the potential to develop periodontal disease or those who are currently responding to an infection with A. actinomycetemcomitans .