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The effect of Octapinol on dento‐gingival plaque and development of gingivitis
Author(s) -
Willard LarsOlof,
Edwardsson Stig,
Attström Rolf,
Matsson Lars
Publication year - 1983
Publication title -
journal of periodontal research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.31
H-Index - 83
eISSN - 1600-0765
pISSN - 0022-3484
DOI - 10.1111/j.1600-0765.1983.tb00379.x
Subject(s) - gingivitis , beagle , dental plaque , dentistry , molar , chemistry , oral hygiene , medicine
A substituted amino‐alcohol (Octapinol) with lipophilic‐hydrophilic properties and with a surface tension in water. Solution of about 40 dynes per cm and a comparatively low antibacterial effect against aerobes was tested with respect to its ability to inhibit plaque formation on extracted human molars in an Experimental Plaque System (EPS). A complete plaque inhibition was seen in the teeth treated with Octapinol during the experimental periods varying from 3 to 12 days, while a heavy plaque accumulation was seen in the control teeth during the same periods of time. In addition, Octapinol prohibited further plaque development when tested on established plaque, which also was partly disolved in the presence of the compound. Octapinol was also tested in a short‐term study in beagle dogs and demonstrated an ability to reduce plaque formation and the development of gingivitis during an experimental period of 28 days.