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Vascular changes during the development of the rat gingiva
Author(s) -
Goes Mario Fernando,
Almeida Oslei Paes,
Bozzo Lourenço,
Vizioli Mário Roberto
Publication year - 1983
Publication title -
journal of periodontal research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.31
H-Index - 83
eISSN - 1600-0765
pISSN - 0022-3484
DOI - 10.1111/j.1600-0765.1983.tb00376.x
Subject(s) - junctional epithelium , molar , connective tissue , anatomy , interdental consonant , major duodenal papilla , gingival sulcus , medicine , pathology , dentistry
Permeability of the dento‐gingival vessels was studied during the development of the gingiva in rats. Groups of animals, aged 19 to 150 days, were injected intravenously with colloidal carbon, and the gingival vessels were observed both macroscopically and microscopically. As the tooth cusps emerged into the oral cavity, vessels labelled with carbon were observed in the connective tissue overlying the tooth and, two to four days later, tracer particles were found in the vessels adjacent to the junctional epithelium. The leaking vessels had a linear pattern beneath the dento‐gingival junction in young animals, while in adult rats these vessels formed loops. In the interdental papilla, labelled vessels were observed initially only in the gingiva adjacent to the distal of the first molars, and two days later also in the gingiva facing the mesial of the second molars. There was a progressive increase in gingival blood vessels labelled with carbon until the rats were 150 days old. The results indicate that the inflammatory process and the increased vascular permeability in the gingiva are initialed during tooth eruption and show quantitative and morphological modifications during the organization of the sulcular and junctional epithelia.