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Chemotactic activity in periodontal disease
Author(s) -
Okada H.,
Silverman M. S.
Publication year - 1979
Publication title -
journal of periodontal research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.31
H-Index - 83
eISSN - 1600-0765
pISSN - 0022-3484
DOI - 10.1111/j.1600-0765.1979.tb00784.x
Subject(s) - chemotaxis , periodontal disease , complement system , immune system , immunology , complement (music) , chemistry , medicine , microbiology and biotechnology , biology , dentistry , biochemistry , receptor , complementation , gene , phenotype
Extracts of gingival tissue from periodontal patients can generate chemotactic factors from guinea pig serum for mononuclear leukocytes. Both the classical and alternative pathways of complement activation are triggered. The data do not preclude the fact that other components of the gingival extract (bacterial and/or tissue enzymes, immune complexes and endotoxin) may also play a role in the generation of chemotactic factors from complement.