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Calcium deficiency, pregnancy and lactation in rats
Author(s) -
Rasmussen P.
Publication year - 1977
Publication title -
journal of periodontal research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.31
H-Index - 83
eISSN - 1600-0765
pISSN - 0022-3484
DOI - 10.1111/j.1600-0765.1977.tb00146.x
Subject(s) - dental alveolus , bone resorption , osteoporosis , medicine , resorption , mandible (arthropod mouthpart) , calcium , endocrinology , pregnancy , lactation , osteolysis , dentistry , biology , botany , genus , genetics
Adult female rats were subjected to severe calcium deprivation by feeding them a calciumdeficient diet containing oxalate (Test group a), and in addition by subjecting them to pregnancy and lactation (Test group b). The effect on the mandible of the present regimen was that of typical osteoporosis. Great amounts of bone tissue had been removed from the endosteal aspects of the bone, while the periosteal surfaces were almost intact, leaving the mandibular outline close to the normal. Alveolar bone loss did not seem exceptional when compared to the mandibular body. Bone resorption had occurred mostly on lamina dura. Horizontal bone loss was observed in a few cases where the gingival tissues were inflamed. The bone loss seemed to have been mediated by osteoclasts as well as mononuclear, hypertrophied, elongated cells, the former mostly in the alveolar process, the latter in the spongiosa and the endosteal cortical bone of the mandibular body. No signs of osteocytic osteolysis could be observed.