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Two years oral use of chlorhexidine in man
Author(s) -
Nuki Klaus,
Schlenker R.,
Löue H.,
Rindom Schiöutt C.
Publication year - 1976
Publication title -
journal of periodontal research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.31
H-Index - 83
eISSN - 1600-0765
pISSN - 0022-3484
DOI - 10.1111/j.1600-0765.1976.tb00066.x
Subject(s) - chlorhexidine , medicine , dentistry , biopsy , lactic dehydrogenase , dehydrogenase , placebo , glycolysis , enzyme , chemistry , pathology , biochemistry , metabolism , alternative medicine
Ultramicrochemical methods were used to assay lactic dehydrogenase, (L.D.H.) malic dehydrogenase (M.D.H.) and glucose‐6‐phosphate dehydrogenase (G‐6‐P.D.H.) in biopsy specimens obtained from palatal mucosa and gingiva of young human volunteers. Half the specimens examined came from individuals who had used a chlorhexidine containing mouthrinse for 18 months and the other half from individuals using a placebo mouthrinse. There were no statistically significant differences in enzyme activity between the two groups. It is concluded that the activities of the glycolytic processes investigated, confirm the lack of any chronic inflammatory process in the chlorhexidine exposed tissue.