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Experimental periodontal disease in rats induced by plaque‐forming microorganisms
Author(s) -
Hoeven J. S.,
Mikx F. H. M.,
Plasschaert A. J. M.,
Maltha J. C.
Publication year - 1975
Publication title -
journal of periodontal research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.31
H-Index - 83
eISSN - 1600-0765
pISSN - 0022-3484
DOI - 10.1111/j.1600-0765.1975.tb00018.x
Subject(s) - capsule , dental plaque , gingivitis , buccal administration , gingival inflammation , dentistry , periodontal disease , medicine , pathology , microbiology and biotechnology , biology , botany
Three different capsule or extracellular slime producing microorganisms: Rothia, Neisseria and Bacterionema were tested in SPF Osborne‐Mendel rats for their ability to stimulate plaque formation and their effect on the gingiva. Gingival inflammation in the rats was evaluated in histological sections of buccal gingivae. All three the test strains were found to stimulate plaque formation. The high plaque score in the inoculated groups of rats was found to be attended by an increase in the area of infiltrated gingival tissue.