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The effect of various disclosants on plaque accumulation in human subjects
Author(s) -
Goldman R. S.,
Abelson D. C.,
Mandel I. D.,
Chilton N. W.
Publication year - 1974
Publication title -
journal of periodontal research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.31
H-Index - 83
eISSN - 1600-0765
pISSN - 0022-3484
DOI - 10.1111/j.1600-0765.1974.tb00694.x
Subject(s) - saline , medicine , dentistry , oral hygiene , volunteer , gingivitis , dental plaque , agronomy , biology
A clinical trial was designed to evaluate the effect of daily use of three disclosants, erythrosine, fast green and sodium fluorescein, compared to a saline control, on subsequent plaque deposition. Twenty subjects refrained from all oral hygiene for four consecutive 7 day periods. Each subject rinsed each night with a disclosing solution or saline as assigned and according to a design using 5 restricted Latin Squares of 4 subjects each. At 7 day intervals, plaque score (modified Quigley‐Hein, J. Periodontology, 41:41, 1970), plaque weight and absorbance were evaluated and each subject received a rubber cup prophylaxis and another disclosant was assigned. The data revealed no significant differences between the groups of subjects using the various disclosants or saline, demonstrating that daily use of these agents has no effect on rates of plaque formation as determined clinically. There was a statistically significant increase in plaque accumulation (20 %) in all groups by completion of the experiment despite the weekly prophylaxis. All subjects had a moderate to severe gingivitis by the end of the fourth week.