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The effect of hyaluronidase upon epithelium in vitro
Author(s) -
Innes P. B.
Publication year - 1974
Publication title -
journal of periodontal research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.31
H-Index - 83
eISSN - 1600-0765
pISSN - 0022-3484
DOI - 10.1111/j.1600-0765.1974.tb00669.x
Subject(s) - hyaluronidase , in vitro , keratin , epithelium , oral mucosa , mitotic index , chemistry , biology , microbiology and biotechnology , mitosis , biochemistry , anatomy , enzyme , genetics
The effect of hyaluronidase on embryonic chicken skin and mouse oral mucosa has been studied in vitro. Autoradiographic studies showed that .05% hyaluronidase increased the epithelial mitotic index while liquid scintillation techniques demonstrated that hyaluronidase increased the uptake of tritiated thymidine in chicken skin in vitro. Further experiments demonstrated that .05% hyaluronidase interferes with the keratinization process in embryonic chicken skin and mouse oral mucosa in vitro.