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Activation of latent collagenase by microbial plaque
Author(s) -
Robertson Paul B.,
Cobb Charles M.,
Taylor Robert E.,
Fullmer Harold M.
Publication year - 1974
Publication title -
journal of periodontal research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.31
H-Index - 83
eISSN - 1600-0765
pISSN - 0022-3484
DOI - 10.1111/j.1600-0765.1974.tb00657.x
Subject(s) - thermolabile , collagenase , chemistry , microbiology and biotechnology , dental plaque , biochemistry , biology , enzyme
Sterile extracts of whole human microbial plaque released substantial latent collagenolytic activity in gingival collagenase preparations, homogenates of polymorphonuclear leukocytes, and tissue macrophages. The plaque activation factor was thermolabile, nondialyzable, and had essentially no inherent collagenolytic activity.