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Human gingival lipids
Author(s) -
Rabinowitz Joseph L.,
Rutberg M.,
Cohen D.W.,
Marsh J. B.
Publication year - 1973
Publication title -
journal of periodontal research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.31
H-Index - 83
eISSN - 1600-0765
pISSN - 0022-3484
DOI - 10.1111/j.1600-0765.1973.tb00772.x
Subject(s) - sphingomyelin , periodontal disease , dentistry , composition (language) , pathology , chemistry , biology , medicine , biochemistry , cholesterol , linguistics , philosophy
Lipid analyses were performed on gingival biopsies obtained from 28 patients with periodontal disease. For each of the patients studied, biopsies were taken from areas with well‐defined periodontal pathology as well as from areas showing no obvious disease. The individual specimens were assayed for total lipids, neutral and phospholipids, collagen, non‐collagen protein, DNA and RNA. The phospholipids and the neutral lipids were further separated into their individual constituents, and the amount of each and its fatty acid composition was determined. The results were compared between the diseased and non‐diseased samples and with previous results with pig gingiva. No statistically significant differences were evident between diseased and non‐inflammed gingival areas. However, since all patients had been initially treated by scaling, root planing, and personal hygiene for weeks prior to Surgery. it is not possible to conclude that no changes in gingival lipids accompany periodontal disease. In comparison with pig gingival tissue, human tissue showed a higher DNA and non‐collagen protein content on a wet weight basis. All other parameters measured were about the same for the two species except that the sphingomyelin content of human gingiva was lower.