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Historical quantification of the biological effects of estradiol benzoate on the gingiva and gential mucosa of castrated rabbits
Author(s) -
Rlibright William C.,
Higa Leslie H.,
Yan Michael E.
Publication year - 1971
Publication title -
journal of periodontal research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.31
H-Index - 83
eISSN - 1600-0765
pISSN - 0022-3484
DOI - 10.1111/j.1600-0765.1971.tb00588.x
Subject(s) - estradiol benzoate , estrogen , castration , vagina , uterus , oral mucosa , medicine , endocrinology , hormone , pathology , anatomy , ovariectomized rat
The biological effects of castration and estrogen replacement therapy were studied in the gingiva of adult female rabbits. Measurements were made to hislologically quantitate changes induced by estrogen on the gingiva when compared to the well established effects which occur in the reproductive tract of the female rabbit. Parentally administered esradiol benzoate resulted in significant changes within the uterus and vagina. No corresponding changes were detected in the gingiva.