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The affinity of chlorhexidine for hydroxyapatite and salivary mucins
Author(s) -
Rölla Gunnar,
Löe Harald,
Rindom Schiøtt C.
Publication year - 1970
Publication title -
journal of periodontal research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.31
H-Index - 83
eISSN - 1600-0765
pISSN - 0022-3484
DOI - 10.1111/j.1600-0765.1970.tb00698.x
Subject(s) - chlorhexidine , mucin , in vivo , dentistry , tooth surface , microbiology and biotechnology , chemistry , chlorhexidine gluconate , saliva , dental plaque , biofilm , colonization , medicine , bacteria , biology , biochemistry , genetics
This study indicates that chlorhexidine gluconate adsorbs to hydroxyapatite, tooth surfaces and salivary mucins and that the adsorbed chlorhexidine is released when the concentration in the environment is low. The possible formation of reservoirs of chlorhexidine on the tooth surface in vivo from which chlorhexidine is slowly released could, therefore, prevent bacterial colonization and the development of dental plaque.